{"id":580,"date":"2016-04-12T12:58:14","date_gmt":"2016-04-12T15:58:14","guid":{"rendered":"http:\/\/biologo.com.br\/bio\/?p=580"},"modified":"2016-04-12T13:01:22","modified_gmt":"2016-04-12T16:01:22","slug":"zika-virus-prejudica-celulas-do-cerebro-fetal-humano","status":"publish","type":"post","link":"https:\/\/biologo.com.br\/bio\/zika-virus-prejudica-celulas-do-cerebro-fetal-humano\/","title":{"rendered":"Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano"},"content":{"rendered":"

Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano:<\/span><\/strong>\u00a0Pesquisadores brasileiros do Instituto D\u2019Or de Pesquisa e Ensino (IDOR) e da Universidade Federal do Rio de Janeiro (UFRJ) conseguiram correlacionar o Zika v\u00edrus e a ocorr\u00eancia de microcefalia em estudo conjunto iniciado em fevereiro desse ano. <\/span><\/span><\/p>\n

Com os resultados alcan\u00e7ados, ser\u00e1 poss\u00edvel iniciar a identifica\u00e7\u00e3o de medicamentos que poder\u00e3o futuramente conter a situa\u00e7\u00e3o alarmante da doen\u00e7a, especialmente no Brasil.<\/span><\/p>\n

Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano<\/strong><\/span><\/h2>\n
\"Principais<\/a>
Principais sintomas da febre Zika<\/span><\/strong><\/figcaption><\/figure>\n

Descoberta \u00e9 resultado de estudo conjunto de pesquisadores do IDOR e da UFRJ<\/strong><\/p>\n

 <\/p>\n

O estudo foi publicado na revista americana Science<\/a>, uma das mais conceituadas no mundo. <\/span><\/p>\n

Para se ter uma ideia da relev\u00e2ncia desta conquista, em 136 anos de exist\u00eancia, raros foram os trabalhos realizados por cientistas lotados exclusivamente no\u00a0Brasil publicados nesta revista.<\/span><\/p>\n

Correla\u00e7\u00e3o entre o Zika v\u00edrus e a microcefalia.<\/span><\/strong><\/p>\n

\u201cOs organoides cerebrais representam excelentes modelos para a investiga\u00e7\u00e3o de dist\u00farbios de neurodesenvolvimento, uma vez que podem simular no laborat\u00f3rio v\u00e1rias caracter\u00edsticas do crescimento do c\u00e9rebro humano nos ajudando a desvendar os mecanismos de diversas doen\u00e7as e identificar novos tratamentos\u201d, explica Rehen.<\/span><\/p><\/blockquote>\n

Pez\u00e3o corta verba da Ci\u00eancia<\/a><\/span><\/p>\n

\"Zika<\/a>
Aedes aegypti.<\/strong><\/em> Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano<\/span><\/figcaption><\/figure>\n

A partir de c\u00e9lulas-tronco humanas reprogramadas, cientistas liderados pelo Dr. Stevens Rehen, neurocientista do IDOR e da UFRJ, criaram organoides cerebrais, tamb\u00e9m conhecidos como minic\u00e9rebros e similares ao c\u00e9rebro humano em desenvolvimento.<\/span><\/p>\n

O passo seguinte foi infectar estas estruturas com o Zika v\u00edrus a fim de observar as consequ\u00eancias para a forma\u00e7\u00e3o do c\u00e9rebro fetal.<\/span><\/p>\n

O nome Zika tem sua origem na floresta de Zika, perto de Entebbe na Rep\u00fablica de Uganda, onde o v\u00edrus foi isolado pela primeira vez em 1947. \u00c9 relacionado aos v\u00edrus da dengue, da febre amarela e encefalite do Nilo, os quais igualmente fazem parte da fam\u00edlia Flaviviridae.<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano:\u00a0Pesquisadores brasileiros do Instituto D\u2019Or de Pesquisa e Ensino (IDOR) e da Universidade<\/p>\n","protected":false},"author":1,"featured_media":582,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"colormag_page_container_layout":"default_layout","colormag_page_sidebar_layout":"default_layout","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[17],"tags":[],"class_list":["post-580","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biomedicas"],"yoast_head":"\nZika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano - Bi\u00f3logo<\/title>\n<meta name=\"description\" content=\"Zika v\u00edrus prejudica c\u00e9lulas do c\u00e9rebro fetal humano: Descoberta \u00e9 resultado de estudo conjunto de pesquisadores do IDOR e da UFRJ. 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